Fall 2017 Research Report Now Available

Download the latest edition of Research Report by the Lymphoma Research Foundation. More >

FDA approves axicabtagene ciloleucel (YESCARTA™) as first CAR-T cell therapy for certain types of large B-cell lymphoma.

Axicabtagene Ciloleucel (YESCARTA™) is the second gene therapy approved by the FDA and the first for certain types of non-Hodgkin lymphoma (NHL). More >

Register for an Upcoming Education Program

LRF's in-person educational conferences include the National Educational Forum, Regional Lymphoma Workshops and local Ask the Doctor Programs. More >


Welcome to Focus on DLBCL

The FocusOnDLBCL website is designed to provide helpful information and resources to patients, caregivers, physicians, and others affected by diffuse large B-cell lymphoma (DLBCL). From understanding an initial diagnosis - including a patient's genetics and subtype - to learning about treatment options and clinical trials, this website provides the latest information from the world's leading experts in the field.

We invite you to browse the website to learn more about DLBCL.

Getting the Facts

Lymphoma is the most common blood cancer. The two main forms of lymphoma are Hodgkin lymphoma and non-Hodgkin lymphoma (NHL). Diffuse large B-cell lymphoma (DLBCL) accounts for about 30 percent of newly diagnosed cases of NHL in the United States and represents the most common subtype of lymphoma. Lymphoma occurs when cells of the immune system called lymphocytes, a type of white blood cell, grow and multiply uncontrollably. Malignant lymphocytes can travel to many parts of the body, including the lymph nodes, spleen, bone marrow, blood, or other organs, and form a mass called a tumor. The body has two main types of lymphocytes that can develop into lymphomas: B lymphocytes (B-cells) and T lymphocytes (T-cells).

Recent Research

Research into non-Hodgkin lymphoma and in particular DLBCL, the most common subtype of lymphoma, has led to significant advancements in the understanding of the disease. Research continues on multiple fronts to develop better treatments for patients. We hope you will find the information presented here useful in understanding your disease and discussing it with your healthcare team.

Patient Education Programs

The Lymphoma Research Foundation (LRF) is the nation’s largest nonprofit devoted to funding innovative research and serving the lymphoma community through a comprehensive series of education, advocacy and outreach efforts. LRF provides a comprehensive series of educational programs for people with lymphoma and their loved ones, including a number of in-person conferences on the local, regional, and national levels.

DLBCL YouTube Video